The AZURA Pilot Prep LC 250 LPG system is a complete low pressure gradient (LPG) HPLC system for the purification of samples in the laboratory scale. The AZURA Preparative HPLC system is designed and optimized for the purification of milligram to gram samples. The system proposal consists of a preparative HPLC pump with ternary LPG valve block and an Assistent ASM 2.1L. Large sample volumes can be introduced via the third LPG channel. For smal volume size the sample can be injected with a manuel injection valve. The AZURA P 2.1L pump covers a wide flow rate range and pressure capabilities. In the current setup, it supports max. pressures up to 225 bar at flow rates up to 100 ml/min (200 bar from 100 - 220 ml/min). The integrated automatic recognition of the pump head with RFID technology allows fast adaptions of the pump for various applications. The LPG valve block enables the accurate formation of binary or ternary gradients with a maximum flow rate of 220 ml/min. The system is completed by an AZURA assistant ASM 2.1L for preparative HPLC. This assistant includes the detector UVD 2.1S, an injection valve and a 12 port multipositions valve for fractionation. The AZURA HPLC system comes with an eluent tray for safe storage of eluent bottles and an integrated leak management system with sensors. VertexPlus AX columns (20 mm and 30 mm ID) can be attached with an optional AZURA mounting bracket at both sides of each AZURA element. A leak sensor and the capillary guidance as well as the optional Mobile Control with touch screen facilitate the safe and user friendly operation. Modern design with completely demountable fronts turn the system into a visual highlight.